2.1 years ago

david 4.3k

@david_fe

Insulin eye drop may lower IOP and more. Consequently, the FitEyes community has been closely following the news and research on the use of insulin to treat glaucoma. For background, please see these posts:

• Nasal Insulin may fight glaucoma | Ask FitEyes
• Are there any known side effects for Insulin eye drops? | Ask FitEyes
• Insulin eye drops to lower IOP and regenerate retinal ganglion cells | Ask FitEyes

Recently a FitEyes member noticed that all the information regarding insulin eye drops was suddenly removed from a glaucoma research foundation website without any explanation.

Another FitEyes member said:

I was told that I would be able to take part in the Stanford study on insulin eye drops. I was told to expect a phone call and to then be called in for the preliminary evaluation. But then nothing….. No contact whatsoever!

Checking the clinical trial website, we find that the study has stopped early but may start again.

Safety of Topical Insulin Drops for Open-angle Glaucoma - Full Text View - ClinicalTrials.gov

2.6 years ago

Sherry • 70

@sherry

Many of us have a lot of hope on the clinical trials on Insulin eye drop. It is suspicious that Glaucoma.org suddenly deleted all the information including video on insulin eye drop without any explanation.

If insulin eye drop is not effective, normally the message should be conveyed as ineffective instead of removing all the messages.

Some friends and I are researching all the possible ways to regenerate optic nerves and insulin eye drop has been the most prominent way. We have researched almost all the research and documents on insulin eye drop from google and it seems so far that it is the most safe and hopeful way. We even didn't find any document about serious side effect if dosage is fine.

2.6 years ago

ghost • 0

@ghost

NCT05206877Stanford，Recruitment Status : Not yet recruiting。NCT04118920 Montreal，Recruitment Status : Suspended (Pending regulatory authority clearance)

2.1 years ago

david 4.3k

@david_fe

I am sharing an update from a FitEyes member via the email discussion group. He says:

Apparently the original trial of insulin drops for glaucoma sponsored by U of Montreal and conducted at Stanford was suspended and continues suspended. [See previous answers here for details.]

However, Stanford started another trial in May 2022 led by the same investigator Dr. Jeff Goldberg, and this time they are sponsoring it themselves. That must mean that Stanford really believes in this treatment. This is very promising!

They plan to end collecting data for the phase 1 by Dec 2023. Kind of slow but better than what was going on in 2019 or 2020.

Their contact is Mariana Nunez, MD

1-650-497-7846 mnunez1@stanford.edu

Topical Insulin for Glaucoma - Full Text View - ClinicalTrials.gov

The U of Montreal was doing the trial on its own but it is suspended. It only admitted Quebec residents.

Safety of Topical Insulin Drops for Open-angle Glaucoma - Full Text View - ClinicalTrials.gov

I hope Stanford is successful and brings this treatment to the pharmacy as soon as possible. This is the most promising treatment I have ever read about because it safely regenerated the lost retinal cells and reversed vision loss to glaucoma lab animals, something never done before to my knowledge.